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Single dose epidural hydromorphone in labour pain: maternal pharmacokinetics and neonatal exposure

INTRODUCTION: Epidural hydromorphone could be useful in obstetric analgesia as there is a need for a more water-soluble opioid than sufentanil or fentanyl with prolonged analgesic effect. To our knowledge, the pharmacokinetics of epidural hydromorphone has not been evaluated in parturients. MATERIAL...

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Publicat a:Eur J Clin Pharmacol
Autors principals: Puhto, Terhi, Kokki, Merja, Hakomäki, Henriikka, Spalding, Michael, Gunnar, Teemu, Alahuhta, Seppo, Vakkala, Merja
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306027/
https://ncbi.nlm.nih.gov/pubmed/32363420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-020-02880-6
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