Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12

BACKGROUND/AIM: Steatohepatitis drives fibrogenesis in alcoholic liver disease. However, recent studies have suggested that hepatic stellate cells (HSC) may regulate the parenchymal cell injury and inflammation that precedes liver fibrosis, although the mechanism remains incompletely defined. Neurop...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Arab, Juan P., Cabrera, Daniel, Sehrawat, Tejasav S., Jalan-Sakrikar, Nidhi, Verma, Vikas K., Simonetto, Douglas, Cao, Sheng, Yaqoob, Usman, Leon, Jonathan, Freire, Mariela, Vargas, Jose I., De Assuncao, Thiago M., Kwon, Jung H., Guo, Yi, Kostallari, Enis, Cai, Qing, Kisseleva, Tatiana, Oh, Youngman, Arrese, Marco, Huebert, Robert C., Shah, Vijay H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305991/
https://ncbi.nlm.nih.gov/pubmed/32087348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2020.02.005
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