Inhibitory Effects of Nordihydroguaiaretic acid (NDGA) on the IGF-1 Receptor and Androgen Dependent Growth of LAPC-4 Prostate Cancer Cells

BACKGROUND: Nordihydroguaiaretic acid (NDGA) is an inhibitor of the IGF-1 receptor (IGF-1R) in breast and other cancers, and concomitantly inhibits tumor growth both in cultured cells and animals. The current study evaluates the effect of NDGA on the androgen-stimulated growth of human prostate canc...

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發表在:Prostate
Main Authors: Ryan, Charles, Zavodovskaya, Marianna, Youngren, Jack F., Campbell, Michael, Diamond, Marc, Jones, Jeremy, Shiry, Laura, Allan, Geoffrey, Maddux, Betty A., Goldfine, Ira D.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305632/
https://ncbi.nlm.nih.gov/pubmed/18491370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20789
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