Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors with Altered Sleep Homeostasis and Dopamine D(2)R-mediated Sleep Reduction

Individuals with the neuropsychiatric disorder mania exhibit hyperactivity, elevated mood, and a decreased need for sleep. The brain areas and neuronal populations involved in mania-like behaviors, however, have not been elucidated. In this study, we found that ablating the ventral medial midbrain/p...

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Vydáno v:iScience
Hlavní autoři: Honda, Takato, Takata, Yohko, Cherasse, Yoan, Mizuno, Seiya, Sugiyama, Fumihiro, Takahashi, Satoru, Funato, Hiromasa, Yanagisawa, Masashi, Lazarus, Michael, Oishi, Yo
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305386/
https://ncbi.nlm.nih.gov/pubmed/32563157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101240
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