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Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion

OBJECTIVE: Deletion of Translin (Tsn) from mice induces an unusual metabolic profile characterized by robust adiposity, normal body weight and glucose tolerance. Translin (TN) protein and its partner, trax (TX), form the TN/TX microRNA-degrading enzyme. Since the microRNA system plays a prominent ro...

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Xehetasun bibliografikoak
Argitaratua izan da:Mol Metab
Egile Nagusiak: Fu, Xiuping, Shah, Aparna P., Li, Zhi, Li, Mengni, Tamashiro, Kellie L., Baraban, Jay M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305343/
https://ncbi.nlm.nih.gov/pubmed/32408014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101013
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