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Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion

OBJECTIVE: Deletion of Translin (Tsn) from mice induces an unusual metabolic profile characterized by robust adiposity, normal body weight and glucose tolerance. Translin (TN) protein and its partner, trax (TX), form the TN/TX microRNA-degrading enzyme. Since the microRNA system plays a prominent ro...

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Vydáno v:Mol Metab
Hlavní autoři: Fu, Xiuping, Shah, Aparna P., Li, Zhi, Li, Mengni, Tamashiro, Kellie L., Baraban, Jay M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305343/
https://ncbi.nlm.nih.gov/pubmed/32408014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101013
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