Deletion of translin (Tsn) induces robust adiposity and hepatic steatosis without impairing glucose tolerance

OBJECTIVE: Translin knockout (KO) mice display robust adiposity. Recent studies indicate that translin and its partner protein, trax, regulate the microRNA and ATM kinase signaling pathways, both of which have been implicated in regulating metabolism. In the course of characterizing the metabolic pr...

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Pubblicato in:Int J Obes (Lond)
Autori principali: Shah, Aparna P., Johnson, Miranda D., Fu, Xiuping, Boersma, Gretha J., Shah, Madhura, Wolfgang, Michael J., Tamashiro, Kellie L., Baraban, Jay M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629527/
https://ncbi.nlm.nih.gov/pubmed/30647452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-018-0315-7
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