Deletion of translin (Tsn) induces robust adiposity and hepatic steatosis without impairing glucose tolerance

OBJECTIVE: Translin knockout (KO) mice display robust adiposity. Recent studies indicate that translin and its partner protein, trax, regulate the microRNA and ATM kinase signaling pathways, both of which have been implicated in regulating metabolism. In the course of characterizing the metabolic pr...

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Bibliographic Details
Published in:Int J Obes (Lond)
Main Authors: Shah, Aparna P., Johnson, Miranda D., Fu, Xiuping, Boersma, Gretha J., Shah, Madhura, Wolfgang, Michael J., Tamashiro, Kellie L., Baraban, Jay M.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629527/
https://ncbi.nlm.nih.gov/pubmed/30647452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-018-0315-7
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