Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing

Profiling immunoglobulin (Ig) receptor repertoires with specialized assays can be cost-ineffective and time-consuming. Here we report ImReP, a computational method for rapid and accurate profiling of the Ig repertoire, including the complementary-determining region 3 (CDR3), using regular RNA sequen...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Mandric, Igor, Rotman, Jeremy, Yang, Harry Taegyun, Strauli, Nicolas, Montoya, Dennis J., Van Der Wey, William, Ronas, Jiem R., Statz, Benjamin, Yao, Douglas, Petrova, Velislava, Zelikovsky, Alex, Spreafico, Roberto, Shifman, Sagiv, Zaitlen, Noah, Rossetti, Maura, Ansel, K. Mark, Eskin, Eleazar, Mangul, Serghei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305308/
https://ncbi.nlm.nih.gov/pubmed/32561710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16857-7
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