Exposure–response analysis of endoxifen serum concentrations in early-breast cancer

PURPOSE: Tamoxifen is part of endocrine therapy in breast cancer treatment. Studies have indicated the use of endoxifen concentrations, tamoxifen active metabolite, to guide tamoxifen efficacy. Three endoxifen thresholds have been suggested (5.9 ng/ml, 5.2 ng/ml and 3.3 ng/ml) for therapeutic drug m...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Sanchez-Spitman, Anabel Beatriz, Moes, Dirk-Jan A. R., Swen, Jesse J., Dezentjé, Vincent O., Lambrechts, Diether, Neven, Patrick, Gelderblom, Hans, Guchelaar, Henk-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305085/
https://ncbi.nlm.nih.gov/pubmed/32468081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04089-x
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