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The pore size of mesoporous silica nanoparticles regulates their antigen delivery efficiency
Subunit vaccines generally proceed through a 4-step in vivo cascade—the DUMP cascade—to generate potent cell-mediated immune responses: (1) drainage to lymph nodes; (2) uptake by dendritic cells (DCs); (3) maturation of DCs; and (4) Presentation of peptide-MHC I complexes to CD8(+) T cells. How the...
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| Publicado no: | Sci Adv |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Association for the Advancement of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7304990/ https://ncbi.nlm.nih.gov/pubmed/32596445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz4462 |
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