Dysregulation of the MMP/TIMP Proteolytic System in Subependymal Giant Cell Astrocytomas in Patients With Tuberous Sclerosis Complex: Modulation of MMP by MicroRNA-320d In Vitro

Tuberous sclerosis complex (TSC), a rare genetic disorder caused by a mutation in the TSC1 or TSC2 gene, is characterized by the growth of hamartomas in several organs. This includes the growth of low-grade brain tumors, known as subependymal giant cell astrocytomas (SEGA). Previous studies have sho...

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Publicat a:J Neuropathol Exp Neurol
Autors principals: Bongaarts, Anika, de Jong, Jody M, Broekaart, Diede W M, van Scheppingen, Jackelien, Anink, Jasper J, Mijnsbergen, Caroline, Jansen, Floor E, Spliet, Wim G M, den Dunnen, Wilfred F A, Gruber, Victoria E, Scholl, Theresa, Hainfellner, Johannes A, Feucht, Martha, Borkowska, Julita, Kotulska, Katarzyna, Jozwiak, Sergiusz, Grajkowska, Wieslawa, Buccoliero, Anna Maria, Caporalini, Chiara, Giordano, Flavio, Genitori, Lorenzo, Scicluna, Brendon P, Schouten-van Meeteren, Antoinette Y N, van Vliet, Erwin A, Mühlebner, Angelika, Mills, James D, Aronica, Eleonora
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304985/
https://ncbi.nlm.nih.gov/pubmed/32472129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlaa040
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