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A Fast and Clean BTK Inhibitor

Bruton’s tyrosine kinase (BTK) is a major drug target for B-cell related malignancies; however, existing BTK inhibitors approved for cancer treatment have significant off-targets that limit their use for autoimmune and inflammatory diseases. Remibrutinib (LOU064) is a novel covalent BTK inhibitor th...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Gabizon, Ronen, London, Nir
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304894/
https://ncbi.nlm.nih.gov/pubmed/32401033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c00597
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