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Assessing Site-Specific Enhancements Imparted by Hyperpolarized Water in Folded and Unfolded Proteins by 2D HMQC NMR

[Image: see text] Hyperpolarized water can be a valuable aid in protein NMR, leading to amide group (1)H polarizations that are orders of magnitude larger than their thermal counterparts. Suitable procedures can exploit this to deliver 2D (1)H–(15)N correlations with good resolution and enhanced sen...

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Publicat a:J Am Chem Soc
Autors principals: Szekely, Or, Olsen, Gregory Lars, Novakovic, Mihajlo, Rosenzweig, Rina, Frydman, Lucio
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304870/
https://ncbi.nlm.nih.gov/pubmed/32338002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c00807
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