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Distinctive germline expression of class I human leukocyte antigen (HLA) alleles and DRB1 heterozygosis predict the outcome of patients with non-small cell lung cancer receiving PD-1/PD-L1 immune checkpoint blockade

BACKGROUND: Nivolumab is a human monoclonal antibody against programmed cell death receptor-1 (PD-1) able to rescue quiescent tumor infiltrating cytotoxic T lymphocytes (CTLs) restoring their ability to kill target cells expressing specific tumor antigen-derived epitope peptides bound to homologue h...

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Detaylı Bibliyografya
Yayımlandı:J Immunother Cancer
Asıl Yazarlar: Correale, Pierpaolo, Saladino, Rita Emilena, Giannarelli, Diana, Giannicola, Rocco, Agostino, Rita, Staropoli, Nicoletta, Strangio, Alessandra, Del Giudice, Teresa, Nardone, Valerio, Altomonte, Maria, Pastina, Pierpaolo, Tini, Paolo, Falzea, Antonia Consuelo, Imbesi, Natale, Arcati, Valentina, Romeo, Giuseppa, Caracciolo, Daniele, Luce, Amalia, Caraglia, Michele, Giordano, Antonio, Pirtoli, Luigi, Necas, Alois, Amler, Evzen, Barbieri, Vito, Tassone, Pierfrancesco, Tagliaferri, Pierosandro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304840/
https://ncbi.nlm.nih.gov/pubmed/32554614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000733
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