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Fermentable fiber-induced hepatocellular carcinoma in mice recapitulates gene signatures found in human liver cancer

Hepatocellular carcinoma (HCC), the most malignant form of primary liver cancer, is the fourth most prevalent cause of cancer mortality globally. It was recently discovered that the dietary fermentable fiber, inulin, can reprogram the murine liver to favor HCC development in a gut microbiota-depende...

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Publicado en:PLoS One
Autores principales: Chandrashekar, Darshan Shimoga, Golonka, Rachel M., Yeoh, Beng San, Gonzalez, David J., Heikenwälder, Mathias, Gerwirtz, Andrew T., Varambally, Sooryanarayana, Vijay-Kumar, Matam
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304627/
https://ncbi.nlm.nih.gov/pubmed/32559205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234726
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