The CNS-specific proteoglycan, brevican, and its ADAMTS4-cleaved fragment show differential serological levels in Alzheimer’s disease, other types of dementia and non-demented controls: A cross-sectional study

Evidence indicate that the brain-specific protein, brevican, is proteolytically cleaved during neurodegeneration, hence positioning fragments of brevican as potential blood biomarkers of neurodegenerative diseases, such as dementia. We aimed to develop two assays capable of detecting the brevican N-...

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Publicat a:PLoS One
Autors principals: Jonesco, Ditte S., Karsdal, Morten A., Henriksen, Kim
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304580/
https://ncbi.nlm.nih.gov/pubmed/32559242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234632
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