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A caspase-6-cleaved fragment of Glial Fibrillary Acidic Protein as a potential serological biomarker of CNS injury after cardiac arrest

Blood levels of Glial Fibrillary Acidic protein (GFAP) reflect processes associated with different types of CNS injury. Evidence suggests that GFAP is cleaved by caspases during CNS injury, hence positioning GFAP fragments as potential biomarkers of injury-associated processes. We set out to develop...

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Pubblicato in:PLoS One
Autori principali: Jonesco, Ditte S., Hassager, Christian, Frydland, Martin, Kjærgaard, Jesper, Karsdal, Morten, Henriksen, Kim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834260/
https://ncbi.nlm.nih.gov/pubmed/31693684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224633
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