Control of the neuroprotective Lipocalin Apolipoprotein D expression by alternative promoter regions and differentially expressed mRNA 5’ UTR variants

The Lipocalin Apolipoprotein D (ApoD) is one of the few genes consistently overexpressed in the aging brain, and in most neurodegenerative and psychiatric diseases. Its functions include metabolism regulation, myelin management, neuroprotection, and longevity regulation. Knowledge of endogenous regu...

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Опубликовано в: :PLoS One
Главные авторы: Diez-Hermano, Sergio, Mejias, Andres, Sanchez, Diego, Gutierrez, Gabriel, Ganfornina, Maria D.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304576/
https://ncbi.nlm.nih.gov/pubmed/32559215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234857
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