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Control of the neuroprotective Lipocalin Apolipoprotein D expression by alternative promoter regions and differentially expressed mRNA 5’ UTR variants

The Lipocalin Apolipoprotein D (ApoD) is one of the few genes consistently overexpressed in the aging brain, and in most neurodegenerative and psychiatric diseases. Its functions include metabolism regulation, myelin management, neuroprotection, and longevity regulation. Knowledge of endogenous regu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Diez-Hermano, Sergio, Mejias, Andres, Sanchez, Diego, Gutierrez, Gabriel, Ganfornina, Maria D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304576/
https://ncbi.nlm.nih.gov/pubmed/32559215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234857
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