טוען...

Toxicity induced by a bispecific T cell redirecting protein is mediated by both T cells and myeloid cells in immunocompetent mice()

Bispecific T cell engagers have demonstrated clinical efficacy, however, their use can be accompanied by severe toxicity. Mechanistic understanding of these toxicities is limited by a lack of suitable immunocompetent pre-clinical models. Here, we describe an immunocompetent mouse tumor model which e...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Immunol
Main Authors: Godbersen-Palmer, Claire, Coupet, Tiffany A., Grada, Zakaria, Zhang, Samuel C., Sentman, Charles L.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304495/
https://ncbi.nlm.nih.gov/pubmed/32295875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901401
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!