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Macrophages and Associated Ligands in the Aged Injured Nerve: A Defective Dynamic That Contributes to Reduced Axonal Regrowth

The regenerative capacity of injured peripheral nerves is diminished with aging. To identify factors that contribute to this impairment, we compared the immune cell response in young vs. aged animals following nerve injury. First, we confirmed that macrophage accumulation is delayed in aged injured...

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Bibliographische Detailangaben
Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Stratton, Jo Anne, Eaton, Shane, Rosin, Nicole L., Jawad, Sana, Holmes, Alexandra, Yoon, Grace, Midha, Rajiv, Biernaskie, Jeff
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304384/
https://ncbi.nlm.nih.gov/pubmed/32595489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.00174
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