Macrophages and Associated Ligands in the Aged Injured Nerve: A Defective Dynamic That Contributes to Reduced Axonal Regrowth

The regenerative capacity of injured peripheral nerves is diminished with aging. To identify factors that contribute to this impairment, we compared the immune cell response in young vs. aged animals following nerve injury. First, we confirmed that macrophage accumulation is delayed in aged injured...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Aging Neurosci
Main Authors: Stratton, Jo Anne, Eaton, Shane, Rosin, Nicole L., Jawad, Sana, Holmes, Alexandra, Yoon, Grace, Midha, Rajiv, Biernaskie, Jeff
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304384/
https://ncbi.nlm.nih.gov/pubmed/32595489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.00174
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