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Macrophages and Associated Ligands in the Aged Injured Nerve: A Defective Dynamic That Contributes to Reduced Axonal Regrowth

The regenerative capacity of injured peripheral nerves is diminished with aging. To identify factors that contribute to this impairment, we compared the immune cell response in young vs. aged animals following nerve injury. First, we confirmed that macrophage accumulation is delayed in aged injured...

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Pubblicato in:Front Aging Neurosci
Autori principali: Stratton, Jo Anne, Eaton, Shane, Rosin, Nicole L., Jawad, Sana, Holmes, Alexandra, Yoon, Grace, Midha, Rajiv, Biernaskie, Jeff
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304384/
https://ncbi.nlm.nih.gov/pubmed/32595489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.00174
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