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Directed Evolution Using Stabilized Bacterial Peptide Display

Chemically stabilized peptides have attracted intense interest by academics and pharmaceutical companies due to their potential to hit currently ‘undruggable’ targets. However, engineering an optimal sequence, stabilizing linker location, and physicochemical properties is a slow and arduous process....

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Navaratna, Tejas, Atangcho, Lydia, Mahajan, Mukesh, Subramanian, Vivekanandan, Case, Marshall, Min, Andrew, Tresnak, Daniel, Thurber, Greg M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7304070/
https://ncbi.nlm.nih.gov/pubmed/31880439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b10716
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