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A Dual-Purpose Linker for Alpha Helix Stabilization and Imaging Agent Conjugation to Glucagon-Like Peptide-1 Receptor Ligands

Peptides display many characteristics of efficient imaging agents such as rapid targeting, fast background clearance, and low non-specific cellular uptake. However, poor stability, low affinity, and loss of binding after labeling often preclude their use in vivo. Using the glucagon-like peptide-1 re...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Zhang, Liang, Navaratna, Tejas, Liao, Jianshan, Thurber, Greg M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933591/
https://ncbi.nlm.nih.gov/pubmed/25594741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc500584t
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