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Determining Free-Energy Differences Through Variationally Derived Intermediates

[Image: see text] Free-energy calculations based on atomistic Hamiltonians and sampling are key to a first-principles understanding of biomolecular processes, material properties, and macromolecular chemistry. Here, we generalize the free-energy perturbation method and derive nonlinear Hamiltonian t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Chem Theory Comput
Prif Awduron: Reinhardt, Martin, Grubmüller, Helmut
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2020
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303968/
https://ncbi.nlm.nih.gov/pubmed/32392408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.0c00106
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