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Sacituzumab govitecan: Antibody-drug conjugate in triple negative breast cancer and other solid tumors

Patients with metastatic triple negative breast cancer (mTNBC) that has progressed on first-line therapy have a poor prognosis with limited therapeutic options. Sacituzumab govitecan (SG) is a novel antibody-drug conjugate (ADC) that has shown promising efficacy in mTNBC. SG is comprised of SN-38, t...

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Podrobná bibliografie
Vydáno v:Drugs Today (Barc)
Hlavní autoři: Fenn, Kathleen M., Kalinsky, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303962/
https://ncbi.nlm.nih.gov/pubmed/31584574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1358/dot.2019.55.9.3039669
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