Club Cell Heme Oxygenase-1 Deletion: Effects in Hyperoxia-Exposed Adult Mice

Thioredoxin reductase-1 (TXNRD1) inhibition activates nuclear factor (erythroid-derived 2)-like 2 (Nrf2) responses and prevents acute lung injury (ALI). Heme oxygenase-1 (HO-1) induction following TXNRD1 inhibition is Nrf2-dependent in airway epithelial (club) cells in vitro. The influence of club c...

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Udgivet i:Oxid Med Cell Longev
Main Authors: Dunigan-Russell, Katelyn, Silverberg, Mary, Lin, Vivian Y., Li, Rui, Wall, Stephanie B., Li, Qian, Nicola, Teodora, Gotham, John, Crowe, David R., Vitiello, Peter F., Agarwal, Anupam, Tipple, Trent E.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303751/
https://ncbi.nlm.nih.gov/pubmed/32587658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2908271
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