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3Scover: Identifying Safeguard TF from Cell Type-TF Specificity Network by an Extended Minimum Set Cover Model

Transcription factors (TFs) define cellular identity either by activating target cell program or by silencing donor program as demonstrated by intensive cell reprogramming studies. Here, we propose an extended minimum set cover model with stable selection (3Scover) to systematically identify silenci...

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Publicat a:iScience
Autors principals: Yuan, Qiuyue, Wang, Yong
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303665/
https://ncbi.nlm.nih.gov/pubmed/32554189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101227
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