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3Scover: Identifying Safeguard TF from Cell Type-TF Specificity Network by an Extended Minimum Set Cover Model

Transcription factors (TFs) define cellular identity either by activating target cell program or by silencing donor program as demonstrated by intensive cell reprogramming studies. Here, we propose an extended minimum set cover model with stable selection (3Scover) to systematically identify silenci...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Yuan, Qiuyue, Wang, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303665/
https://ncbi.nlm.nih.gov/pubmed/32554189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101227
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