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The phosphodiesterase-4 and glycine transporter-1 inhibitors enhance in vivo hippocampal theta network connectivity and synaptic plasticity, whereas D-serine does not

Dysfunctional N-methyl-D-aspartate receptors (NMDARs) and cyclic adenosine monophosphate (cAMP) have been associated with deficits in synaptic plasticity and cognition found in neurodegenerative and neuropsychiatric disorders such as Alzheimer’s disease (AD) and schizophrenia. Therapeutic approaches...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Ahnaou, A., Broadbelt, T., Biermans, R., Huysmans, H., Manyakov, N. V., Drinkenburg, W. H. I. M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303193/
https://ncbi.nlm.nih.gov/pubmed/32555167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-00875-6
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