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Ultrafine silicon dioxide nanoparticles cause lung epithelial cells apoptosis via oxidative stress-activated PI3K/Akt-mediated mitochondria- and endoplasmic reticulum stress-dependent signaling pathways
Silicon dioxide nanoparticles (SiO(2)NPs) are widely applied in industry, chemical, and cosmetics. SiO(2)NPs is known to induce pulmonary toxicity. In this study, we investigated the molecular mechanisms of SiO(2)NPs on pulmonary toxicity using a lung alveolar epithelial cell (L2) model. SiO(2)NPs,...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7303152/ https://ncbi.nlm.nih.gov/pubmed/32555254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66644-z |
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