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Regulatory T cells specifically suppress conventional CD8αβ T cells in intestinal tumors of APC(Min/+) mice

The presence of activated T cells in colorectal cancer tissues is a strong predictor of patient survival. Our previous studies have shown that regulatory T cells (Treg) are able to reduce T cell transendothelial migration in vitro and accumulation of effector T cells in intestinal tumors in vivo in...

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Bibliografiske detaljer
Udgivet i:Cancer Immunol Immunother
Main Authors: Szeponik, Louis, Akeus, Paulina, Rodin, William, Raghavan, Sukanya, Quiding-Järbrink, Marianne
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303072/
https://ncbi.nlm.nih.gov/pubmed/32185408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02540-9
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