Upregulated immuno-modulator PD-L1 in malignant peripheral nerve sheath tumors provides a potential biomarker and a therapeutic target

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are rare aggressive sarcomas with poor prognosis. More than half of MPNSTs develop from benign precursor tumors associated with neurofibromatosis type 1 (NF1) which is a tumor suppressor gene disorder. Early detection of malignant transfo...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Immunol Immunother
Auteurs principaux: Farschtschi, Said, Kluwe, Lan, Park, Su-Jin, Oh, Su-Jun, Mah, Nancy, Mautner, Victor-Felix, Kurtz, Andreas
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2020
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303069/
https://ncbi.nlm.nih.gov/pubmed/32193699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02548-1
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