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Alternaria toxins as casein kinase 2 inhibitors and possible consequences for estrogenicity: a hybrid in silico/in vitro study

Emerging mycotoxins produced by Alternaria spp. were previously reported to exert cytotoxic, genotoxic, but also estrogenic effects in human cells. The involved mechanisms are very complex and not fully elucidated yet. Thus, we followed an in silico target fishing approach to extend knowledge on the...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Aichinger, Georg, Dellafiora, Luca, Pantazi, Foteini, Del Favero, Giorgia, Galaverna, Gianni, Dall’Asta, Chiara, Marko, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7303061/
https://ncbi.nlm.nih.gov/pubmed/32328700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02746-x
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