Inhibition of urea transporter ameliorates uremic cardiomyopathy in chronic kidney disease

Uremic cardiomyopathy, characterized by hypertension, cardiac hypertrophy, and fibrosis, is a complication of chronic kidney disease (CKD). Urea transporter (UT) inhibition increases the excretion of water and urea, but the effect on uremic cardiomyopathy has not been studied. We tested UT inhibitio...

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Publicat a:FASEB J
Autors principals: Kuma, Akihiro, Wang, Xiaonan H., Klein, Janet D., Tan, Lin, Naqvi, Nawazish, Rianto, Fitra, Huang, Ying, Yu, Manshu, Sands, Jeff M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302978/
https://ncbi.nlm.nih.gov/pubmed/32367640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000214RR
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