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Urea Transport and Clinical Potential of Urearetics

PURPOSE OF REVIEW: Urea is transported by urea transporter proteins in kidney, erythrocytes, and other tissues. Mice in which different urea transporters have been knocked-out have urine concentrating defects, which has led to the development and testing of UT-A and UT-B inhibitors as urearetics. Th...

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Detalhes bibliográficos
Publicado no:Curr Opin Nephrol Hypertens
Main Authors: Klein, Janet D., Sands, Jeff M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974121/
https://ncbi.nlm.nih.gov/pubmed/27367911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNH.0000000000000252
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