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Age and Ischemia Differentially Impact Mitochondrial Ultrastructure and Function in a Novel Model of Age-Associated Estrogen-Deficiency in the Female Rat Heart

Altered mitochondrial respiration, morphology, and quality control collectively contribute to mitochondrial dysfunction in the aged heart. Because myocardial infarction remains the leading cause of death in aged women, the present study utilized a novel rodent model to recapitulate human menopause t...

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Detalhes bibliográficos
Publicado no:Pflugers Arch
Main Authors: Garvin, Alexandra M., Aurigemma, Nicole C., Hackenberger, Jenna L., Korzick, Donna H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302907/
https://ncbi.nlm.nih.gov/pubmed/28776263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-017-2034-7
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