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Quantitative proteomic analysis reveals novel mitochondrial targets of estrogen deficiency in the aged female rat heart

The incidence of myocardial infarction rises sharply at menopause, implicating a potential role for estrogen (E(2)) loss in age-related increases in ischemic injury. We aimed to identify quantitative changes to the cardiac mitochondrial proteome of aging females, based on the hypothesis that E(2) de...

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Detalhes bibliográficos
Main Authors: Lancaster, T. S., Jefferson, S. J., Hunter, J. Craig, Lopez, Veronica, Van Eyk, J. E., Lakatta, E. G., Korzick, D. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472466/
https://ncbi.nlm.nih.gov/pubmed/22930739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00184.2011
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