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Clinicopathologic characteristics of resectable colorectal cancer with mismatch repair protein defects in Chinese population: Retrospective case series and literature review

Colorectal cancer (CRC) represents a major malignancy globally, with microsatellite instability as its second top molecular mechanism of carcinogenesis. Immunohistochemical (IHC), whose sensitivity and specificity exceed 90%, is used routinely to detect 4 MMR proteins (MLH1, PMS2, MSH2, and MSH6) fo...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Li, Jingjing, Xu, Qi, Luo, Cong, Chen, Lei, Ying, Jieer
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302659/
https://ncbi.nlm.nih.gov/pubmed/32541478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000020554
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