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Effects of macrophage depletion on characteristics of cervix remodeling and pregnancy in CD11b-dtr mice

To test the hypothesis that macrophages are essential for remodeling the cervix in preparation for birth, pregnant homozygous CD11b-dtr mice were injected with diphtheria toxin (DT) on days 14 and 16 postbreeding. On day 15 postbreeding, macrophages (F4/80+) were depleted in cervix and kidney, but n...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biol Reprod
Hauptverfasser: Yellon, S M, Greaves, E, Heuerman, A C, Dobyns, A E, Norman, J E
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302510/
https://ncbi.nlm.nih.gov/pubmed/30629144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/ioz002
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