Semicarbazide-sensitive amine oxidase inhibition ameliorates albuminuria and glomerulosclerosis but does not improve tubulointerstitial fibrosis in diabetic nephropathy

Semicarbazide-sensitive amine oxidase (SSAO) is an enzyme with a unique dual function in controlling inflammation as well as reactive oxygen species (ROS) generation. We have demonstrated benefit of SSAO inhibition in acute kidney fibrosis. However the function of SSAO in chronic kidney disease (CKD...

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Publicat a:PLoS One
Autors principals: Wong, May YW, Saad, Sonia, Wong, Muh Geot, Stangenberg, Stefanie, Jarolimek, Wolfgang, Schilter, Heidi, Zaky, Amgad, Gill, Anthony, Pollock, Carol
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302447/
https://ncbi.nlm.nih.gov/pubmed/32555665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234617
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