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Current understanding of adult neurogenesis in the mammalian brain: how does adult neurogenesis decrease with age?

Adult neurogenesis occurs throughout life in restricted brain regions in mammals. However, the number of neural stem cells (NSCs) that generate new neurons steadily decreases with age, resulting in a decrease in neurogenesis. Transplantation of mesenchymal cells or cultured NSCs has been studied as...

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Bibliographic Details
Published in:Inflamm Regen
Main Authors: Kase, Yoshitaka, Shimazaki, Takuya, Okano, Hideyuki
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302355/
https://ncbi.nlm.nih.gov/pubmed/32566044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41232-020-00122-x
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