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Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling

Neurogenesis in specific brain regions in adult mammals decreases with age. Progressive reduction in the proliferation of neural stem and progenitor cells (NS/PCs) is a primary cause of this age-associated decline. However, the mechanism responsible for this reduction is poorly understood. We identi...

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Опубликовано в: :Stem Cell Reports
Главные авторы: Kase, Yoshitaka, Otsu, Kinya, Shimazaki, Takuya, Okano, Hideyuki
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565990/
https://ncbi.nlm.nih.gov/pubmed/31080114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.010
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