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Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling

Neurogenesis in specific brain regions in adult mammals decreases with age. Progressive reduction in the proliferation of neural stem and progenitor cells (NS/PCs) is a primary cause of this age-associated decline. However, the mechanism responsible for this reduction is poorly understood. We identi...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Kase, Yoshitaka, Otsu, Kinya, Shimazaki, Takuya, Okano, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565990/
https://ncbi.nlm.nih.gov/pubmed/31080114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.04.010
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