Suppression of Mig-6 overcomes the acquired EGFR-TKI resistance of lung adenocarcinoma

BACKGROUND: The resistance of lung cancer to epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) is one of the unconquered frontiers in chemotherapy. Mitogen-inducible gene 6 (Mig-6) is known to inhibit the kinase activity of epidermal growth factor receptor (EGFR). Similarly, nume...

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Vydáno v:BMC Cancer
Hlavní autoři: Kang, Da Hyun, Jung, Sung Soo, Yeo, Min-Kyung, Lee, Da Hye, Yoo, Geon, Cho, Sang Yeon, Oh, In-Jae, Kim, Ju-Ock, Park, Hee Sun, Chung, Chaeuk, Lee, Jeong Eun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302243/
https://ncbi.nlm.nih.gov/pubmed/32552717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07057-z
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