SARS-CoV-2-specific T cells exhibit unique features reflecting robust helper function, lack of terminal differentiation, and high proliferative potential

Convalescing COVID-19 patients mount robust T cell responses against SARS-CoV-2, suggesting an important role for T cells in viral clearance. To date, the phenotypes of SARS-CoV-2-specific T cells remain poorly defined. Using 38-parameter CyTOF, we phenotyped longitudinal specimens of SARS-CoV-2-spe...

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Gepubliceerd in:bioRxiv
Hoofdauteurs: Neidleman, Jason, Luo, Xiaoyu, Frouard, Julie, Xie, Guorui, Gill, Gurjot, Stein, Ellen S., McGregor, Matthew, Ma, Tongcui, George, Ashley, Kosters, Astrid, Greene, Warner C., Vasquez, Joshua, Ghosn, Eliver, Lee, Sulggi, Roan, Nadia R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302219/
https://ncbi.nlm.nih.gov/pubmed/32577663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.08.138826
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