Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

The emergence of SARS-CoV-2 and the ensuing explosive epidemic of COVID19 disease has generated a need for assays to rapidly and conveniently measure the antiviral activity of SARSCoV-2-specific antibodies. Here, we describe a collection of approaches based on SARS-CoV-2 spike-pseudotyped, single-cy...

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Bibliografiska uppgifter
I publikationen:bioRxiv
Huvudupphovsmän: Schmidt, Fabian, Weisblum, Yiska, Muecksch, Frauke, Hoffmann, Hans-Heinrich, Michailidis, Eleftherios, Lorenzi, Julio C. C., Mendoza, Pilar, Rutkowska, Magdalena, Bednarski, Eva, Gaebler, Christian, Agudelo, Marianna, Cho, Alice, Wang, Zijun, Gazumyan, Anna, Cipolla, Melissa, Caskey, Marina, Robbiani, Davide F., Nussenzweig, Michel C., Rice, Charles M., Hatziioannou, Theodora, Bieniasz, Paul D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302213/
https://ncbi.nlm.nih.gov/pubmed/32577658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.08.140871
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