Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

The emergence of SARS-CoV-2 and the ensuing explosive epidemic of COVID19 disease has generated a need for assays to rapidly and conveniently measure the antiviral activity of SARSCoV-2-specific antibodies. Here, we describe a collection of approaches based on SARS-CoV-2 spike-pseudotyped, single-cy...

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Publicado en:bioRxiv
Autores principales: Schmidt, Fabian, Weisblum, Yiska, Muecksch, Frauke, Hoffmann, Hans-Heinrich, Michailidis, Eleftherios, Lorenzi, Julio C. C., Mendoza, Pilar, Rutkowska, Magdalena, Bednarski, Eva, Gaebler, Christian, Agudelo, Marianna, Cho, Alice, Wang, Zijun, Gazumyan, Anna, Cipolla, Melissa, Caskey, Marina, Robbiani, Davide F., Nussenzweig, Michel C., Rice, Charles M., Hatziioannou, Theodora, Bieniasz, Paul D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302213/
https://ncbi.nlm.nih.gov/pubmed/32577658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.08.140871
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