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SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins.

Tightly packed complexes of nucleocapsid protein and genomic RNA form the core of viruses and may assemble within viral factories, dynamic compartments formed within the host cells. Here, we examine the possibility that the multivalent RNA-binding nucleocapsid protein (N) from the severe acute respi...

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Bibliografiske detaljer
Udgivet i:bioRxiv
Main Authors: Perdikari, Theodora Myrto, Murthy, Anastasia C., Ryan, Veronica H., Watters, Scott, Naik, Mandar T., Fawzi, Nicolas L.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302208/
https://ncbi.nlm.nih.gov/pubmed/32577653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.09.141101
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