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Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19

The global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the associated disease COVID-19, requires therapeutic interventions that can be rapidly identified and translated to clinical care. Traditional drug discovery methods have a >90% failure rate and can take 1...

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Publicado en:bioRxiv
Autores principales: Mirabelli, Carmen, Wotring, Jesse W., Zhang, Charles J., McCarty, Sean M., Fursmidt, Reid, Frum, Tristan, Kadambi, Namrata S., Amin, Anya T., O’Meara, Teresa R., Pretto, Carla D., Spence, Jason R., Huang, Jessie, Alysandratos, Konstantinos D., Kotton, Darrell N., Handelman, Samuel K., Wobus, Christiane E., Weatherwax, Kevin J., Mashour, George A., O’Meara, Matthew J., Sexton, Jonathan Z.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302203/
https://ncbi.nlm.nih.gov/pubmed/32577649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.05.27.117184
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