Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19

The global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the associated disease COVID-19, requires therapeutic interventions that can be rapidly identified and translated to clinical care. Traditional drug discovery methods have a >90% failure rate and can take 1...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Mirabelli, Carmen, Wotring, Jesse W., Zhang, Charles J., McCarty, Sean M., Fursmidt, Reid, Frum, Tristan, Kadambi, Namrata S., Amin, Anya T., O’Meara, Teresa R., Pretto, Carla D., Spence, Jason R., Huang, Jessie, Alysandratos, Konstantinos D., Kotton, Darrell N., Handelman, Samuel K., Wobus, Christiane E., Weatherwax, Kevin J., Mashour, George A., O’Meara, Matthew J., Sexton, Jonathan Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302203/
https://ncbi.nlm.nih.gov/pubmed/32577649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.05.27.117184
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