Combination therapy of BCR-ABL-positive B cell acute lymphoblastic leukemia by tyrosine kinase inhibitor dasatinib and c-JUN N-terminal kinase inhibition

BACKGROUND: The Philadelphia chromosome (Ph), which leads to the creation and expression of the fusion gene product BCR-ABL, underlines the pathogenesis of chronic myelogenous leukemia (CML) and a fraction of adult and pediatric acute B-lymphoblastic leukemia (B-ALL). The BCR-ABL tyrosine kinase inh...

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Xiao, Xinhua, Liu, Ping, Li, Donghe, Xia, Zhizhou, Wang, Peihong, Zhang, Xiuli, Liu, Mingzhu, Liao, Lujian, Jiao, Bo, Ren, Ruibao
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7302132/
https://ncbi.nlm.nih.gov/pubmed/32552902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00912-3
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