Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2

We remain largely without effective prophylactic/therapeutic interventions for COVID-19. Although many human clinical trials are ongoing, there remains a deficiency of supportive preclinical drug efficacy studies. Here we assessed the prophylactic/therapeutic efficacy of hydroxychloroquine (HCQ), a...

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Veröffentlicht in:bioRxiv
Hauptverfasser: Rosenke, Kyle, Jarvis, Michael A., Feldmann, Friederike, Schwarz, Benjamin, Okumura, Atsushi, Lovaglio, Jamie, Saturday, Greg, Hanley, Patrick W., Meade-White, Kimberly, Williamson, Brandi N., Hansen, Frederick, Perez-Perez, Lizette, Leventhal, Shanna, Tang-Huau, Tsing-Lee, Nason, Martha, Callison, Julie, Haddock, Elaine, Scott, Dana, Sewell, Graham, Bosio, Catharine M., Hawman, David, de Wit, Emmie, Feldmann, Heinz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7301902/
https://ncbi.nlm.nih.gov/pubmed/32577633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.10.145144
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